As cancer is a multifactorial disease, the multimodal action of microRNAs makes them an attractive tool for novel therapeutic approaches.The tumor suppressive miR-7-5p has been shown to act on many aspects of oncogenesis, including cell proliferation, migration and angiogenesis, by targeting a spectrum of key genes.We developed a synthetic chemical

This paper presents an analysis on the effect of support springs in an ends circular hollow sections welded into a YT joint.The overall behavior and failure of the joint were characterized under axial compression of the lap Vertical Rectangle Wooden Plaque brace.Two joint failure modes were identified: chord wall plastification (Mode A) and cross-s

This article analyzes the memories of traumatic experiences held by major characters in two contemporary Vietnamese American novels: Lan Throat Caos Monkey Bridge and Le Thi Diem Thuys The Gangster We Are All Looking For.Because the parents who experienced trauma during the Vietnam War refuse to share their haunting pasts with the coming-of-age nar

Chronic refractory wounds are one of the most serious complications of diabetes, and the effects of common treatments are limited.Chiral hydrogel combined with dimethyloxalyglycine (DMOG) as a dressing is a promising strategy for the treatment of chronic wounds.In this research, we have developed a DMOG-loaded supramolecular chiral amino-acid-deriv